diff --git a/Modules/FindGTK2.cmake b/Modules/FindGTK2.cmake
index fe3716551..c443ca094 100644
--- a/Modules/FindGTK2.cmake
+++ b/Modules/FindGTK2.cmake
@@ -414,7 +414,7 @@ function(_GTK2_ADJUST_LIB_VARS _var)
             set_property(TARGET GTK2::${_basename} APPEND PROPERTY INTERFACE_INCLUDE_DIRECTORIES "${GTK2_${_var}_INCLUDE_DIR}")
         endif()
 
-        if(GTK2_${_var}CONFIG_INCLUDE_DIR)
+        if(GTK2_${_var}CONFIG_INCLUDE_DIR AND NOT "${GTK2_${_var}CONFIG_INCLUDE_DIR}" STREQUAL "GTK2_${_var}_INCLUDE_DIR")
             set_property(TARGET GTK2::${_basename} APPEND PROPERTY INTERFACE_INCLUDE_DIRECTORIES "${GTK2_${_var}CONFIG_INCLUDE_DIR}")
         endif()