diff --git a/Modules/FindQt4.cmake b/Modules/FindQt4.cmake
index 24747f732..28b84543d 100644
--- a/Modules/FindQt4.cmake
+++ b/Modules/FindQt4.cmake
@@ -1203,6 +1203,10 @@ if (QT_QMAKE_EXECUTABLE AND QTVERSION)
       "${QT_MKSPECS_DIR}/default"
       ${QT_INCLUDE_DIR}
   )
+  set_property(TARGET Qt4::QtCore APPEND PROPERTY
+    INTERFACE_COMPILE_DEFINITIONS
+      $<$<NOT:$<CONFIG:Debug>>:QT_NO_DEBUG>
+  )
   set_property(TARGET Qt4::QtCore PROPERTY
     INTERFACE_QT_MAJOR_VERSION 4
   )