diff --git a/Modules/UseQt4.cmake b/Modules/UseQt4.cmake
index 9ce475cb7..dbe28ac54 100644
--- a/Modules/UseQt4.cmake
+++ b/Modules/UseQt4.cmake
@@ -21,6 +21,9 @@ SET_PROPERTY(DIRECTORY APPEND PROPERTY COMPILE_DEFINITIONS_DEBUG QT_DEBUG)
 SET_PROPERTY(DIRECTORY APPEND PROPERTY COMPILE_DEFINITIONS_RELEASE QT_NO_DEBUG)
 SET_PROPERTY(DIRECTORY APPEND PROPERTY COMPILE_DEFINITIONS_RELWITHDEBINFO QT_NO_DEBUG)
 SET_PROPERTY(DIRECTORY APPEND PROPERTY COMPILE_DEFINITIONS_MINSIZEREL QT_NO_DEBUG)
+IF(NOT CMAKE_CONFIGURATION_TYPES AND NOT CMAKE_BUILD_TYPE)
+  SET_PROPERTY(DIRECTORY APPEND PROPERTY COMPILE_DEFINITIONS QT_NO_DEBUG)
+ENDIF()
 
 INCLUDE_DIRECTORIES(${QT_INCLUDE_DIR})